Research Fellow in Enzyme Engineering / Synthetic Biology (EcoCTs)

A Post-Doctoral position in enzyme engineering/synthetic biology is available within EcoCTs, a [email protected] Intra-CREATE project between the French National Centre for Scientific Research (CNRS) and A*STAR – Singapore Institute of Food and Biotechnology Innovation (SIFBI) platform, and SynCTI-NUS in Singapore.

The successful candidate will be a key member of an ambitious research project at the forefront of the Synthetic Biology field, funded by the National Research Foundation (NRF) within the frame of [email protected] that associates Toulouse Biotechnology Institute (INSA, CNRS, INRAE) in France and A*STAR-SIFBI, and SynCTI-NUS in Singapore. Within this project, we aim to address knowledge-based bottlenecks along the value chain from Engineering Biology to Industrial Biotechnology. The goal is to develop a platform workflow that integrates enzyme design, pathway and cell engineering for maximising performance in bioreactors that would be applicable to any new bio-production in line with sustainable circular-bioeconomy.  This challenge will be addressed in 3 workpackages:

1/- Enzyme optimization and spatial disposition for pathway design,
2/- Development of new experimental and computational methods for Pathway Design and optimization,
3/- Development of integrated experimental and computational methods for bioprocess optimization.

Candidates are required to have:

  • PhD in Molecular Biology, Biochemistry, Biochemical engineering or related field.
  • Experience with enzyme engineering and enzyme library construction
  • Expertise with HT screening, assay design and development and trouble shooting
  • Experience in structural biology and molecular modelling/computational enzyme design would be a plus
  • Preferred experience with protein production, purification, characterization and crystallization knowledge
  • Preferred experience with metabolic engineering/synthetic biology background
  • Strong communication and organizational skills and enjoy working in a team-oriented environment.
  • Good English skills are required.

For more information on the position and how to apply, visit [email protected].

Research Assistant (Biotechnology)

A Research Assistant position is available in the DNA and RNA Editing (DaRE) Laboratory at the School of Chemical and Biomedical Engineering (SCBE) in NTU. The laboratory, led by Assoc Prof Tan Meng How, works on developing and applying cutting edge biotechnologies, including high throughput sequencing and CRISPR, to read and write genomes and transcriptomes in living cells.

The Research Assistant will be involved in efforts to develop and apply new methodologies to engineer nucleic acids and to push the boundaries of synthetic biology.

Key Responsibilities:

  • Perform research on genomic technologies and explore new biotechnological applications
  • Assist in experiments and data analysis
  • Contribute to the writing of a manuscript, a new grant application, or a technology disclosure or patent

Job Requirements:

  • ​Possess a bachelor’s degree (with honors) in biomedical engineering, bioengineering, biological sciences, or a related discipline
  • Demonstrated experience in scientific research, especially in areas related to biomedical engineering, genomics, synthetic biology, or CRISPR
  • Strong knowledge of the latest genomic technologies

Interested applicants are invited to apply​ at NTU Website.